ATTENUATED VASODILATOR EFFECTIVENESS OF PROTEASE-ACTIVATED RECEPTOR 2 AGONIST IN HETEROZYGOUS PAR2 KNOCKOUT MICE.

Attenuated vasodilator effectiveness of protease-activated receptor 2 agonist in heterozygous par2 knockout mice.

Studies of homozygous PAR2 gene knockout mice have described a mix of phenotypic effects in vitro and in vivo.However, there have been few studies of PAR2 heterozygous (wild-type/knockout; PAR2-HET) mice.The phenotypes of many hemi and heterozygous transgenic mice have been described as intermediates between those of wild-type and knockout animals.

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Comments about the appraisal of systematic reviews in restorative dentistry [version 2; peer review: 2 approved, 1 approved with reservations]

Adequate adoption of evidence-based practice is deeply rooted in accessing methodological navy drapery fabric quality and completeness of systematic reviews and meta-analyses reporting.Nonetheless, this assumption might be flawed if the methodological quality assessment has not been properly conducted.Taking the former statement into consideration,

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Experimental Study to Investigate Effect of Pitch Ratio and Number of Blades on Hydrodynamic Performance of Surface Piercing Propellers

Surface piercing propellers are special supercavitation propellers operating at free surface.These propellers are designed to have the best performance at the highest speed.The geometric parameters of the number of blades and the pitch ratio will significantly impact the critical advance coefficient range, ventilation and consequently the hydrodyna

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